I can work in a lot of different environments. I generally find it quite easy to tune out voices. I can listen to music, work in front of the TV, work with the radio on, work in a cafe, etc.
Yet it is absolutely impossible for me to focus when my kids are nearby. The sounds of toys dropping, banging, and clunking plus the high pitch voices are just too much for my mental filters.
That is why I don’t work from home.